I would think so provided the weight is heavy enough.I started StrongLifts 5x5 with CBL. SL 5x5 is similar to Starting Strength.I've gained about 15 lb. in 6 weeks and can tell a good part of it was muscle.Checked my 1-Rep Max on the lifts before starting so I could set the weight properly.For example, my squat 1RM ended up being 320 lb. So I started the 5x5 program at 185 and went up 5 lb. each session. Just hit 255 for 5x5 this week on the squat. Nothing magical about 185, just thought it was a good weight to start from.Since the weight wasn't real high compared to my 1RM in the beginning I followed the Strength Accumulation (SA) protocol for CBL. Once the weights got heavier and I could feel that I wasn't recovering as much between sessions I switched over to the Density Bulking (DB) protocol. On week 5 (last week) I only got 1 session in, but I'm back on track this week. Happy with my progress thus far. Best thing will be to just get in and try it. If your not happy with how things are going you can try tweaking the backloads to find what works best. You'll just have to monitor your progress bodyfat and strength-wise for feedback and find what works best for you.

This is sound advice. I would supplement SS with more accessory exercises, but that's me. Besides, CBL is a much better option than that retarded GOMAD they suggest (or was it for SL?), and less boring too. It's basically a matter of switching between SA and DB and finding out how your body reacts to it. As Russel said, experimentation is key. We are all unique little snowflakes, at least when it comes to diet/training.