What does Kiefer mean..?

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  • #3612

    kaelanstrength
    Keymaster

    Hey guys, just wondering if someone could explain what Kiefer means when he says “When the body is in an energy surplus, fructose can bypass the rate-limiting steps that preventglucose from creating infinite levels of fat."Thanks

    #77276

    I'm assuming that If muscle and liver glycogen are full. That fructose can gain access into fat storage where glucose would not be able to. I have no idea how or why but that was my interpretation and reasoning to why we limit fructose in the backload. Just my 0.2

    #77277

    Fairy
    Guest

    I think Dave's right. Something along those lines. In any case, avoid fructose!

    #77279

    Drap
    Member

    Fructose only gets stored in the liver, about 20 grams and it's topped out. Anymore and it is re-dickulously easy to store as fat. So limiting is a good idea

    #77278

    Lasse Elsbak
    Participant

    See the video “sugar the bitter truth” on youtube. Lustig explains the process well. 🙂

    #77280

    One thing to understand is that glucose is ready to go. Once its in your body different areas can use it as is.Fructose on the other hand cannot be used right away. Your muscle don't know what to do with it.Fructose goes right to the liver where it will be processed. It cannot be used right away.That may have something to do with it...

    #77281

    business
    Guest

    I'd avoid fructose I know first hand I completely f'd up my prep eating crap like pop tarts and other stuff with high fructose corn syrup and it made me fat fast!! I went from hard 4% bf to soft 7-9% bf in a week worth of back loading so be advise and choose your cho sources wisely

    #77282

    Defiance
    Member

    #77283

    CptSmash
    Member

    Hey guys, just wondering if someone could explain what Kiefer means when he says "When the body is in an energy surplus, fructose can bypass the rate-limiting steps that preventglucose from creating infinite levels of fat."Thanks

    Fructose is one of the only substrates that is predominately metabolized in the liver by PFK-6, which is a step down in the rate limiting step for glucose (hexookinase).  Anyway, that's what Keifer means...the fructose that you eat in small amounts is okay, like in nature you might get some berries or a small piece of fruit.  However, if you get a large load of fructose it is able to bypass glucose in the liver, that is rate limited by hexokinase (it stops the production of glucose, if it has too much).  So you have a lot of fructose, you get a lot of substrate, which if you have excess it will turn into citrate upon entering into the Kreb cycle, whereas increased levels of citrate via the pentose pathway (unsure on this one, can't remember exactly).  Anyway, the increased levels of citrate can get turned into fatty acids from that pathway if you have excess, substrate.One thing unusual about fructose is that it doesn't stimulate a lot of insulin secretion.  However, most fructose also has a lot of glucose, which if fructose dominates the liver, glucose increases insulin, you are essentially overloading the liver with fructose--which makes substrates in an out of control fashion, glucose is locked up in the liver and increases to high levels of blood sugar and insulin, and insulin acts on receptor sites to  store everything away.  What do you get?  Lots of storage in fat cells and a buildup of glucose and fatty acids in the liver (ie. fatty liver leads to liver damage).

    #77284

    Lesli Bortz
    Participant

    please forgive the possibly stupid question about to come…is lactose the same? I know it's not as ideal as glucose and I put it in the same category as fructose as a 50/50 but is it better or worse than fructose or just different?

    #77285

    plaquex
    Member

    Fructose only gets stored in the liver, about 20 grams and it's topped out. Anymore and it is re-dickulously easy to store as fat. So limiting is a good idea

    Afaik the liver can store around 150g of glycogen.So, after fasting a long time your liver glycogen will be depleted. After RT some of your muscle glycogen will also be "gone"/used -> Having stuff with fructose as the first meal in the backload to make sure your liver can get some off it?! Seems like the best idea to me when you want to have something with fructose/HFCS/etc.

    #77286

    bioengineer
    Guest

    please forgive the possibly stupid question about to come...is lactose the same? I know it's not as ideal as glucose and I put it in the same category as fructose as a 50/50 but is it better or worse than fructose or just different?

    Hey - since lactose is a disaccharides, lactase enzyme breaks lactose into galactose and glucose. The galactose is then metabolized to a shitton of various downstream metabolites. As long as lactase is produced fine in your body, you'll be ok. If not, or if you're worried, pick up some lactose digestion support...it's pretty cheap stuff.Alex

    #77287

    All I know is that I decided to give an all dairy carb-backload plus 2 cups white rice one time Lactaid and all! let's just say the family wont let me do that again, couldn't even blame that night on the dog…:/

    #77288

    bioengineer
    Guest

    bahaha must have been a real bowl-buster. :-X :-[ ???

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What does Kiefer mean..?

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