Brown Adipose Tissue activation by Ephedrine.

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  • #5702

    Taken from the newest issue of FLEX magazine, Jan. 2013, page 92:"In a randomized, double-blinded, crossover trial, they administered 2.5mg/kg of oral ephedrine to nine lean and nine obese young men (ephedrine is sold in 10mg doses).  In this study, they gave 170mg of ephedrine for lean subjects and 287.5mg ephedrine for obese subjects.  Shockingly, they found that the ephedrine activates BAT in the majority of lean, but not obese people.  The really interesting fact is that ephedrine did activate brown adipose tissue in lean individuals whereas in the past scientists did not even know if this was possible in humans."... "BAT is a potent stimulator of thermogenesis."REFERENCE: Snyder, B.J., J of Strength Cond Res., 2012 Sep; 26(9):2394-400.Cory

    #122713

    Fairy
    Guest

    Cool 🙂 Cold showers also work!

    #122712

    Cool 🙂 Cold showers also work!

    So I've read.  😉Cory

    #122714

    Brandon D Christ
    Participant

    I wouldn't mind some brown fat, the increased cold tolerance would come in handy for my job.  Coal mines can get awfully cold.

    #122715

    TokyoLifter
    Member

    Taken from the newest issue of FLEX magazine, Jan. 2013, page 92:"In a randomized, double-blinded, crossover trial, they administered 2.5mg/kg of oral ephedrine to nine lean and nine obese young men (ephedrine is sold in 10mg doses).  In this study, they gave 170mg of ephedrine for lean subjects and 287.5mg ephedrine for obese subjects.  Shockingly, they found that the ephedrine activates BAT in the majority of lean, but not obese people.  The really interesting fact is that ephedrine did activate brown adipose tissue in lean individuals whereas in the past scientists did not even know if this was possible in humans."... "BAT is a potent stimulator of thermogenesis."REFERENCE: Snyder, B.J., J of Strength Cond Res., 2012 Sep; 26(9):2394-400.Cory

    170mg of ephedrine??????The fact that ephedrine activates BAT is old.

    #122716

    Taken from the newest issue of FLEX magazine, Jan. 2013, page 92:"In a randomized, double-blinded, crossover trial, they administered 2.5mg/kg of oral ephedrine to nine lean and nine obese young men (ephedrine is sold in 10mg doses).  In this study, they gave 170mg of ephedrine for lean subjects and 287.5mg ephedrine for obese subjects.  Shockingly, they found that the ephedrine activates BAT in the majority of lean, but not obese people.  The really interesting fact is that ephedrine did activate brown adipose tissue in lean individuals whereas in the past scientists did not even know if this was possible in humans."... "BAT is a potent stimulator of thermogenesis."REFERENCE: Snyder, B.J., J of Strength Cond Res., 2012 Sep; 26(9):2394-400.Cory

    170mg of ephedrine??????The fact that ephedrine activates BAT is old.

    Fair enough, but the study was (apparently) from Sep. 2012.Cory

    #122717

    TokyoLifter
    Member

    Mm, I remember reading a study about this as far back as 2001 or 2002. I am sure it has been known for a long time.

    #122718

    Fairy
    Guest

    Taken from the newest issue of FLEX magazine, Jan. 2013, page 92:"In a randomized, double-blinded, crossover trial, they administered 2.5mg/kg of oral ephedrine to nine lean and nine obese young men (ephedrine is sold in 10mg doses).  In this study, they gave 170mg of ephedrine for lean subjects and 287.5mg ephedrine for obese subjects.  Shockingly, they found that the ephedrine activates BAT in the majority of lean, but not obese people.  The really interesting fact is that ephedrine did activate brown adipose tissue in lean individuals whereas in the past scientists did not even know if this was possible in humans."... "BAT is a potent stimulator of thermogenesis."REFERENCE: Snyder, B.J., J of Strength Cond Res., 2012 Sep; 26(9):2394-400.Cory

    170mg of ephedrine??????The fact that ephedrine activates BAT is old.

    Whoa. Just want to remind people that doses that high are considered near lethal. I thought 125mg was maxing out.

    #122719

    TokyoLifter
    Member

    1982:http://europepmc.org/abstract/MED/6290407Ephedrine, a potential slimming drug, directly stimulates thermogenesis in brown adipocytes via beta-adrenoreceptors.1991:http://europepmc.org/abstract/MED/1885257/reload=0;jsessionid=2VPlRurDmz6pxb0mZYS7.14Peripheral mechanisms of thermogenesis induced by ephedrine and caffeine in brown adipose tissue.1986:http://www.eje-online.org/content/112/3_Suppla/S9.shortThermogenesis in human brown adipose tissue and skeletal muscle induced by sympathomimetic stimulationand so on and so on....

    #122720

    TokyoLifter
    Member

    Whoa. Just want to remind people that doses that high are considered near lethal. I thought 125mg was maxing out.

    All a question of tolerance. I never went over 50mg single dose, but I know a guy who was taking 400mg anally (no joke) before workouts.

    #122721

    Whoa. Just want to remind people that doses that high are considered near lethal. I thought 125mg was maxing out.

    All a question of tolerance. I never went over 50mg single dose, but I know a guy who was taking 400mg anally (no joke) before workouts.

    How was that working for him?Cory

    #122722

    Fairy
    Guest

    Oh my god. Okay, I've heard enough. The lengths people go to.

    #122723

    TokyoLifter
    Member

    How was that working for him?Cory

    Oh it seemed to work very well, absorption speed and rate are top notch that way, LOL.

    #122724

    How was that working for him?Cory

    Oh it seemed to work very well, absorption speed and rate are top notch that way, LOL.

    What a way to supp.  Did he do it himself, or did someone help him with the dosages?  LOL!Cory

    #122725

    TokyoLifter
    Member

    Haha, dude you're going places…. I have no clue and don't want to know...

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Brown Adipose Tissue activation by Ephedrine.

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