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From looking around the site it's apparent that Tim Ferriss may be full of it, but in his book The Four Hour Body he makes these claims about EGCG (Green Tea Flavanols):"Much like ALA, EGCG increases GLUT-4 recruitment to the surface of skeletal muscle cells. Of equal interest, it inhibits GLUT-4 recruitment to fat cells.""EGCG appears to increase programmed cell death (apoptosis) in mature fat cells."He mentions human studies but doesn't cite his sources. My questions are a) has anyone seen any of these human tests that can confirm these claims, and b) would it be a bonus to CNS or CBL to take an EGCG supp? In CNS I know that Kiefer mentions CNS can encourage apoptosis...so if EGCG can help increase this mechanism it would be beneficial, right? Thanks in advance for your input! And I also apologize in advance if this topic has been covered. I tried searching for EGCG but didn't come across any mention of it in this capacity. ;D
Interesting. Would it be beneficial to take a 250-600mg camelia sinensis supplement? 🙂
@TokyoLifter: thanks for the links! They sure look like they support his claims. I'll read up on it more.@38kgToSwoleSHIT: I'm not familiar with this supp. What does it do exactly? :-[
Just buy a box of green tea and drop in a bag or two in the water you drink during the day. I used to always have my gallon of water and drop in a few bags of tea and drink that all day. Boom way cheaper than some supp
Just buy a box of green tea and drop in a bag or two in the water you drink during the day. I used to always have my gallon of water and drop in a few bags of tea and drink that all day. Boom way cheaper than some supp
MUCH cheaper, but far less potent in the actual amount of EGCG
I did some research and found some studies about that topic. I included the link and the conclusion. Some of the studies where only done in animal models. You can get sufficient EGCG if you drink 3 cups fresh green tea. But don't use the one in the bags, that's mostly poor quality.Green Tea Extract (Epigallocatechin gallate)The effects of epigallocatechin-3-gallate on thermogenesis and fat oxidation in obese men: a pilot study.http://www.ncbi.nlm.nih.gov/pubmed/17906192Conclusion: These findings suggest that EGCG alone has the potential to increase fat oxidation in men and may thereby contribute to the anti-obesity effects of green tea. However, more studies with a greater sample size and a broader range of age and BMI are needed to define the optimum dose.Anti-obesity effects of green tea: from bedside to benchhttp://www.ncbi.nlm.nih.gov/pubmed/16470636Conclusion: Green tea, green tea catechins, and epigallocatechin gallate (EGCG) have been demonstrated in cell culture and animal models of obesity to reduce adipocyte differentiation and proliferation, lipogenesis, fat mass, body weight, fat absorption, plasma levels of triglycerides, free fatty acids, cholesterol, glucose, insulin and leptin, as well as to increase beta-oxidation and thermogenesisEffects of Green Tea and EGCG on Cardiovascular and Metabolic Healthhttp://www.jacn.org/content/26/4/373S.longConclusion: Several intervention studies have demonstrated green tea catechins containing 200–300 mg EGCG exert beneficial effects on cardiovascular and metabolic health. Therefore, consistent results from well-designed, long-term intervention studies with standardized green tea products would greatly facilitate our understanding of the benefits of green tea catechins. This could potentially transform a beverage traditionally associated with a number of health benefits into an evidence-based functional food.Body weight loss and weight maintenance in relation to habitual caffeine intake and green tea supplementation.http://www.ncbi.nlm.nih.gov/pubmed/16076989Conclusion: High caffeine intake was associated with weight loss through thermogenesis and fat oxidation and with suppressed leptin in women. In habitual low caffeine consumers, the green tea-caffeine mixture improved WM, partly through thermogenesis and fat oxidation.(270 mg epigallocatechin gallate + 150 mg caffeine per day) Acute effects of epigallocatechin gallate from green tea on oxidation and tissue incorporation of dietary lipids in mice fed a high-fat diet.http://www.ncbi.nlm.nih.gov/pubmed/21750518Conclusions:Anti-obesity effects of EGCG can be explained by a decreased food digestibility affecting substrate metabolism of intestinal mucosa and liver, leading to increased post-prandial fat oxidation and reduced incorporation of dietary lipids into tissues.Green tea (-)-epigallocatechin-3-gallate reduces body weight with regulation of multiple genes expression in adipose tissue of diet-induced obese mice.http://content.karger.com/produktedb/produkte.asp?DOI=10.1159/000214834Conclusion: These results suggest that green tea EGCG effectively reduces adipose tissue mass and ameliorates plasma lipid profiles in high-fat diet-induced obese mice. These effects might be at least partially mediated via regulation of the expression of multiple genes involved in adipogenesis, lipolysis, beta-oxidation and thermogenesis in white adipose tissue.Green tea polyphenol epigallocatechin gallate inhibits adipogenesis and induces apoptosis in 3T3-L1 adipocytes.http://www.ncbi.nlm.nih.gov/pubmed/15976140Conclusion: ONLY CELL MODEL. EGCG increased apoptosis in mature adipocytes, as demonstrated by both laser scanning cytometry and terminal deoxynucleotidyl transferase dUTP nick-end labeling assays. Furthermore, EGCG dose-dependently inhibited lipid accumulation in maturing preadipocytes.These results demonstrate that EGCG can act directly to inhibit differentiation of preadipocytes and to induce apoptosis of mature adipocytes and, thus, could be an important adjunct in the treatment of obesity.Novel treatments for obesity and osteoporosis: targeting apoptotic pathways in adipocytes.http://www.ncbi.nlm.nih.gov/pubmed/16178781Conclusion: Rodents. Adipocyte apoptosis has also been induced in vitro using tumor necrosis factor-alpha (TNF-alpha), (-)-epigallocatechin gallate (EGCG) from Camellia sinensis and ajoene, from Allium sativum. Natural products have potential for inducing apoptosis of adipose tissue, inhibiting bone marrow adipogenesis and increasing the expression of osteogenic factors in bone, thereby yielding effective treatments for obesity and osteoporosis.I do write about newest research on my blog. http://www.my-energy-plan.comYou can follow me on twitter or facebook.
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