Hey Kevin,The only downside to capsules is that you are limited by their size and ya usually need to pop several to reach your required amount. For example – they’ll usually be around 500mg for a cap and if you want to take 5 grams of Leucine, that means downing 10 capsules. If ya don’t like sucking down caps, that might pose a problem. For myself personally, I don’t have any problems with pills/caps but simply choose the powder as it’s cheaper/serving. Capsules cost more and you’ll burn through a bottle of it in no time if your consuming 5,10 or 15 grams a/day of Leucine.Hope this helps.PJ